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Stem Cells and Human Diseases / edited by Rakesh Srivastava, Sharmila Shankar

データ種別 電子ブック
著者標目 Srivastava, Rakesh editor
Shankar, Sharmila editor
SpringerLink (Online service)
出版情報 製作表示:Dordrecht : Springer Netherlands , 2012

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URL 図書館共通

EB006867
9789400728011 禁帯出

書誌詳細を非表示

巻次 ISBN:9789400728011
大きさ X, 630 p : online resource
一般注記 1. Cancer Stem Cells: Biology, Perspectives and Therapeutic Implications -- 2. The Perspectives of Stem Cell-based Therapy in Neurological Diseases -- 3. Stem Cell-based Therapy for Lysosomal Storage Diseases -- 4. Drosophila germline stem cells -- 5. Mesenchymal Stem Cells in Hematopoietic Stem Cell Transplantation -- 6. Cancer Stem Cells in Solid Tumors, Markers and Therapy -- 7. Cancer Stem Cells: Paradigm Shifting or Perishing Concept -- 8. Genomics of Prostate Cancer -- 9. Ischemia, reactive radicals, redox signaling and hematopoietic stem cells -- 10. Cancer stem cell models and role in drug discovery -- 11. Origins of Metastasis-Initiating Cells -- 12. The Reduction of Callus Formation during Bone Regeneration by BMP-2 and Human Adipose Derived Stem Cells -- 13. Stem cells and leukemia -- 14. The role of adult bone marrow derived mesenchymal stem cells, growth factors and scaffolds in the repair of cartilage and bone -- 15. Worth the Weight: Adipose Stem Cells in Human Disease -- 16. Neural crest and Hirschsprung's disease -- 17. Common denominators of self-renewal and malignancy IN neural stem cells and GLIOMA -- 18. Stem-like cells from brain tumours or vice versa? -- 19. Translating Mammary Stem Cell and Cancer Stem Cell Biology to the Clinics -- 20. Breast Cancer Stem Cells -- 21. Translin/TRAX deficiency affects mesenchymal differentiation programs and induces bone marrow failure -- 22. Cancer therapies and Stem cells -- 23. Cancer Stem Cells and Head and Neck Squamous Cell Carcinomas -- 24. The Biology of Lung Cancer Stem Cells -- 25. Stem Cell Characters in Primary and Metastatic Tumour Establishment -- 26. Plasticity of Cancer Stem Cells -- 27. Cross talks among Notch, Wnt, and Hedgehog signaling pathways regulate stem cell characteristics -- 28. Global OMICs profiling and functional analysis of CD44+/CD24- stem-like cells in normal human breast tissue and breast cancer -- 29. Breast Cancer Stem Cells: Isolation, characterization and targeting
There have been major advances in understanding the behavior of stem cells and their roles in tissue regeneration, homeostasis and therapy.  Cancer stem cell hypothesis opened a new opportunity for treating and preventing cancers by targeting cancer stem cells or cancer initiating cells.  An increased understanding of stem cell behavior and biology along with rapid advancement of high throughput screening has led to the discovery and development of novel drugs that control stem cell self-renewal and differentiation.  In near future, these molecules will be very useful for treating and preventing several human diseases.  While progress on the clinical front has been slower than desired, the use of stem cells for tissue regeneration and disease management has great potential in human health. The first decade of the 21st century has brought with it significant progress in our understanding of stem cell or progenitor cells and their role in tissue regeneration and management of human diseases including cancer, neurodegenerative disorders, and heart diseases.  This book covers the current state-of-the-art knowledge on the role of stem cells in tissue regeneration, homeostasis and disease management. Features: Coverage of the biology of stem cell and their role in tissue regeneration and organogenesis. Mechanism-based strategies for stem cell self-renewal and differentiation. Role of cancer stem cells or tumor initiating cells in cancer initiation, progression, relapse and drug resistance. Use of stem cells in treating several human diseases, such as Alzheimer's disease, Parkinson's disease, cancer and diabetes
HTTP:URL=http://dx.doi.org/10.1007/978-94-007-2801-1
件 名 LCSH:Medicine
LCSH:Entomology
LCSH:Literacy
FREE:Biomedicine
FREE:Biomedicine general
FREE:Literacy
FREE:Medicine/Public Health, general
FREE:Entomology
分 類 LCC:R-RZ
DC23:610
書誌ID OB00006868
ISBN 9789400728011

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