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Epigenetic Epidemiology / edited by Karin B. Michels
| データ種別 | 電子ブック |
|---|---|
| 著者標目 | Michels, Karin B editor SpringerLink (Online service) |
| 出版情報 | 製作表示:Dordrecht : Springer Netherlands , 2012 |
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| 巻次 | ISBN:9789400724952 |
|---|---|
| 大きさ | XII, 448 p : online resource |
| 一般注記 | The exploding field of epigenetics is challenging the dogma of traditional Mendelian inheritance. Epigenetics plays an important role in shaping who we are and contributes to our prospects of health and disease. While early epigenetic research focused on plant and animal models and in vitro experiments, population-based epidemiologic studies increasingly incorporate epigenetic components. The relevance of epigenetic marks, such as DNA methylation, genomic imprinting, and histone modification for disease causation has yet to be fully explored. This book covers the basic concepts of epigenetic epidemiology, discusses challenges in study design, analysis, and interpretation, epigenetic laboratory techniques, the influence of of age and environmental factors on shaping the epigenome, the role of epigenetics in the developmental origins hypothesis, and provides the state of the art on the epigenetic epidemiology of various health conditions including childhood syndromes, cancer, infectious diseases, inflammation and rheumatoid arthritis, asthma, autism and other neurodevelopmental disorders, psychiatric disorders, diabetes, obesity and metabolic disorders, and atherosclerosis. With contributions from: Peter Jones, Jean-Pierre Issa, Gavin Kelsey, Robert Waterland, and many other experts in epigenetics! HTTP:URL=http://dx.doi.org/10.1007/978-94-007-2495-2 |
| 件 名 | LCSH:Medicine LCSH:Cancer research LCSH:Human genetics LCSH:Epidemiology FREE:Biomedicine FREE:Cancer Research FREE:Epidemiology FREE:Human Genetics |
| 分 類 | LCC:RC261-271 DC23:614.5999 |
| 書誌ID | OB00006863 |
| ISBN | 9789400724952 |