Mendeley出力
Total Synthesis of Bioactive Natural Products by Palladium-Catalyzed Domino Cyclization of Allenes and Related Compounds / by Shinsuke Inuki
(Springer Theses)
| データ種別 | 電子ブック |
|---|---|
| 著者標目 | *Inuki, Shinsuke author SpringerLink (Online service) |
| 出版者 | (Tokyo : Springer Tokyo) |
| 出版年 | 2012 |
書誌詳細を非表示
| 巻次 | ISBN:9784431540434 |
|---|---|
| 大きさ | XVI, 106 p : online resource |
| 一般注記 | Chapter 1. Total Synthesis of Pachastrissamine (Jaspine B) -- Chapter 2. Total Synthesis of Lysergic Acid, Lysergol, and Isolysergol -- Chapter 3. Conclusions The author has developed novel methodologies for highly efficient construction of functionalized heterocycles by palladium-catalyzed domino/cascade cyclization of allenes and related compounds containing appropriate nucleophilic group(s). Based on these methodologies, enantioselective total syntheses of bioactive natural products, pachastrissamine (26% overall yield in seven steps), lysergic acid (4.0% overall yield in fifteen steps), lysergol (3.6% overall yield in fifteen steps) and isolysergol (8.2% overall yield in eleven steps) have been achieved. These are more facile synthetic route than those previously reported. These findings would contribute to the development of efficient synthetic methods for biologically active compounds containing a complex structure HTTP:URL=http://dx.doi.org/10.1007/978-4-431-54043-4 |
| 件 名 | LCSH:Chemistry LCSH:Bioorganic chemistry LCSH:Catalysis FREE:Chemistry FREE:Bioorganic Chemistry FREE:Catalysis |
| 分 類 | LCC:QD241-441 DC23:547 |
| 書誌ID | OB00007257 |
| ISBN | 9784431540434 |