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Electrocardiography of Laboratory Animals

データ種別 電子ブック
著者標目 *Richig, Jeffrey W.
Sleeper, Meg M.
出版者 Burlington : Elsevier Science
出版年 2013

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URL 図書館共通

EB000065
9780124159365 禁帯出

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巻次 electronic bk. ; ISBN:9780124159990
electronic bk. ; ISBN:0124159990
ISBN:9780124159365
Trade Cloth ; ISBN:0124159362
大きさ 1 online resource (144 pages)
内容注記 Front Cover; Electrocardiography of Laboratory Animals; Copyright Page; Dedication; Contents; Preface; Foreword; Acknowledgements; 1 Electrocardiography in Preclinical Safety; Introduction; Regulatory Guidance versus Good Science versus Rationale Drug Development; What To Do When?; Safety Pharmacology versus Toxicology; Safety Pharmacology Studies: Core-Battery and Second-Tier Testing for Cardiotoxicity; Why Study Electrocardiography Preclinically?; Typical Cardiovascular Safety Pharmacology Designs; Rising-Dose Design; Advantages; Disadvantages; 4-Way Crossover/Latin Square Design
AdvantagesDisadvantages; Cardiotoxicity Endpoints in Toxicology; Regarding ECGs; Serum Enzymes; Postmortem Evaluations; The ECG and Drug Safety; 2 Principles of Electrocardiography; Recording the ECG; Cardiac Conduction and Waveform Genesis; Evaluation of the Electrocardiogram; Transmembrane Action Potentials; Evaluation of Waveforms; Mean Electrical Axis; Equipment Considerations; Cardiac Effects of Systemic Potassium and Calcium Abnormalities; Hypokalemia; Hyperkalemia; Hypocalcemia; Hypercalcemia; 3 Canine Electrocardiography; Introduction; Etiology, Pathophysiology, and Gross Pathology
Rhythm DiagnosisNormal Sinus Rhythm; Sinus Tachycardia; Sinus Bradycardia; Respiratory Sinus Arrhythmia; Premature Atrial Complexes; Atrial Tachycardia (AT); Atrial Fibrillation; Premature Ventricular Complexes; Accelerated Idioventricular Rhythm; Ventricular Tachycardia; Ventricular Flutter, Ventricular Fibrillation; Ventricular Asystole; Atrioventricular Block; Atrial Standstill (Silent Atrium); Sinus Node Dysfunction (Sick Sinus Syndrome, Bradycardia-Tachycardia Syndrome); Ventricular Preexcitation and Macro Reentry; 4 Handling and Restraint of Nonhuman Primates; Cynomolgus and Rhesus
Manual RestraintPhysical Restraint; Machine Setup and Configuration; Lead Placement; Obtaining the Tracing; Chemical Restraint; Tracing Handling and Storage; 5 Electrocardiography of Nonhuman Primates; Fundamental Principles of Electrocardiography; Basic Electrocardiographic Physiology; Cardiac Conduction System and the Electrocardiogram; Electrocardiography of Cynomolgus and Rhesus Monkeys; Introduction; Normal Sinus Rhythm; Normal Variants; Cardiac Arrhythmias; Sinoatrial Arrhythmias; Sinus Tachycardia; Sinus Arrhythmia; Sinoatrial Block and Sinus Arrest; Wandering Pacemaker
Sinus BradycardiaSupraventricular Arrhythmias; Atrial Premature Complexes; Atrial Tachycardia; Atrial Flutter; Atrial Fibrillation; Junctional Premature Contraction; Junctional Tachycardia; Ventricular Arrhythmias; Ventricular Premature Complexes (VPCs); Ventricular Escape Complexes; Terminology; Ventricular Tachycardia; Ventricular Fibrillation; Torsades de Pointes; Ventricular Preexcitation; Abnormalities of Impulse Conduction; Sinoatrial Standstill; First-Degree Atrioventricular Block; Second-Degree Atrioventricular Block; Third-Degree Atrioventricular Block; Bundle Branch Blocks
一般注記 Left Bundle Branch Block
Electrocardiography of Laboratory Animals is the only book covering electrocardiography of laboratory animals, including dogs, mini-pigs, and cynomologus monkeys. As more countries institute requirements for the care of laboratory animals in research, this publication offers an effective standard on performing and analyzing ECGs. Topics covered include safety electrocardiography, toxicology, safety pharmacology, and telemetry. Electrocardiography of Laboratory Animals will assist biological and medical researchers, veterinarians, zoologists, and students in understanding electroc
件 名 LCSH:Veterinary electrocardiography
LCSH:Laboratory animals
FREE:TECHNOLOGY & ENGINEERING / Agriculture / Animal Husbandry
FREE:Electronic books
分 類 DC23:636.088/5
書誌ID OB00006725
ISBN 9780124159990
NCID LB40010893

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